Fluid Resolution & Simulation

The nature of the solve is to be different at different resolutions to a degree. Doubling resolution is common multiple for uprezing to get more detail. However 20x40x20 going to 40x80x40 is a huge jump in the fluids "mind" and the settings will need to be quite different between the two. Where as 100x200x100 to 200x400x200 is going to look close to the same with more detail.
Think of it like a picture 20x40 pixels can't make out what that looks like, 40x80 is now a tall icon and you can see a little more, once you get to a certain rez you can see the full image. Anything more will just be more clear/sharpness to the image. Fluid solve is kinda like that.
Now think about painting an image in photoshop. if you have 20x40 pixels how you paint that image and how you exaggerate colors and contrast to get it to show up and read is quite different then how you would paint it if you had more resolution.
This example is just to say low rez doubled is noticeably more readable where higher rez ends up just having more detail.
(click to enlarge)